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|doi = 10.1136/adc.2006.104448
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}}</ref> As impressive clinical successes with Prontosil started to be reported from all over Europe, and especially after thea widely published treatment in 1936<ref?[Rubin, R. P. (2007). A brief history of great discoveries in pharmacology: In celebration of the centennial anniversary of the founding of the American Society of Pharmacology and Experimental Therapeutics. Pharmacological Reviews, 59(4), 289-359. doi: 10.1124/pr.107.70102]</ref> of [[Franklin Delano Roosevelt, Jr.]]<ref>[http://www.time.com/time/magazine/article/0,9171,771900,00.html Medicine: Prontosil], ''[[TIME Magazine]]'', December 28, 1936 [http://www.webcitation.org/5nAF7xRRv Archived]</ref> (a son of U.S. president [[Franklin D. Roosevelt]]), acceptance was quick and dozens of medicinal chemistry teams set out to improve Prontosil.
==Eclipse and legacy==
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