Neuromedin U receptor 2


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Neuromedin-U receptor 2 is a protein that in humans is encoded by the NMUR2 gene.[5][6][7]

NMUR2
Identifiers
AliasesNMUR2, FM-4, FM4, NMU-R2, NMU2R, TGR-1, TGR1, Neuromedin U receptor 2
External IDsOMIM: 605108; MGI: 2441765; HomoloGene: 49618; GeneCards: NMUR2; OMA:NMUR2 - orthologs
Gene location (Human)
Chromosome 5 (human)
Chr.Chromosome 5 (human)[1]

Chromosome 5 (human)

Genomic location for NMUR2

Genomic location for NMUR2

Band5q33.1Start152,391,546 bp[1]
End152,433,368 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]

Chromosome 11 (mouse)

Genomic location for NMUR2

Genomic location for NMUR2

Band11|11 B1.3Start55,915,813 bp[2]
End55,931,836 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • tibialis anterior muscle

  • testicle

  • mucosa of ileum

  • deltoid muscle

  • corpus callosum

  • skin of thigh

  • C1 segment

  • internal globus pallidus

  • right testis

  • right lung
Top expressed in
  • embryo

  • submandibular gland

  • cervix

  • jejunum

  • duodenum

  • skin of abdomen

  • trachea

  • stomach
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

56923

216749

Ensembl

ENSG00000132911

ENSMUSG00000037393

UniProt

Q9GZQ4

Q8BZ39

RefSeq (mRNA)

NM_020167

NM_153079

RefSeq (protein)

NP_064552

NP_694719

Location (UCSC)Chr 5: 152.39 – 152.43 MbChr 11: 55.92 – 55.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000132911Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037393Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Tate CG, Grisshammer R (Jan 1997). "Heterologous expression of G-protein-coupled receptors". Trends Biotechnol. 14 (11): 426–30. doi:10.1016/0167-7799(96)10059-7. PMID 8940772.
  6. ^ Howard AD, Wang R, Pong SS, Mellin TN, Strack A, Guan XM, Zeng Z, Williams DL Jr, Feighner SD, Nunes CN, Murphy B, Stair JN, Yu H, Jiang Q, Clements MK, Tan CP, McKee KK, Hreniuk DL, McDonald TP, Lynch KR, Evans JF, Austin CP, Caskey CT, Van der Ploeg LH, Liu Q (Jul 2000). "Identification of receptors for neuromedin U and its role in feeding". Nature. 406 (6791): 70–4. doi:10.1038/35017610. PMID 10894543. S2CID 205007370.
  7. ^ "Entrez Gene: NMUR2 neuromedin U receptor 2".
  8. ^ Zheng X, Guo L, Wang D, Deng X (2014). "p-Synephrine: a novel agonist for neuromedin U2 receptor". Biol Pharm Bull. 37 (5): 764–70. doi:10.1248/bpb.b13-00788. PMID 24598981.