Trenbolone: Difference between revisions - Wikipedia

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===Mechanism of action===

It has both [[anabolic]] and [[androgenic]] effects.<ref name="Llewellyn2011" /> Once [[metabolized]], the drugs have the effect of increasing [[ammonium]] ion uptake by muscles, leading to an increase in the rate of [[protein synthesis]]. It may also have the secondary effects of stimulating appetite and decreasing the rate of [[catabolism]], as all [[anabolic steroids]] are believed to; however, catabolism likely increases significantly once the steroid is no longer taken.<ref>http://www.sportsci.org/encyc/anabster/anabster.html{{full citation needed|date=December 2012}}</ref> At least one study in rats has shown trenbolone to cause gene expression of the [[androgen receptor]] at least as potent as [[Dihydrotestosterone|DHTdihydrotestosterone]] (DHT). This evidence tends to indicate trenbolone can cause an increase in male [[secondary sex characteristic]]s without the need to convert to dihydrotestosteroneDHT.<ref>{{cite journal |doi=10.1093/toxsci/70.2.202 |title=In Vitro and in Vivo Effects of 17beta-Trenbolone: A Feedlot Effluent Contaminant |year=2002 |last1=Wilson |first1=V. S. |journal=[[Toxicological Sciences]] |volume=70 |issue=2 |pages=202–11 |pmid=12441365 |last2=Lambright |first2=C |last3=Ostby |first3=J |last4=Gray Jr |first4=LE}}</ref>

===Pharmacokinetics===