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How is CO excreted by the body? If it is at all. Carboxyhemoglobin eventually goes to the liver right, so isn't it eventually urinated out? As with red blood cells? 2ndly, what % of CO we breathe in is excreted out, because I heard someone say a % generally stays in your body for good. But that % is prolly just stuck in the liver, making it harmless? So maybe a % of it is released within years? And the rest urinated out? Thanks. [[Special:Contributions/67.175.224.138|67.175.224.138]] ([[User talk:67.175.224.138|talk]]) 14:32, 7 March 2020 (UTC).

:It is my understanding that the CO remains tightly attached to the carboxyhemoglobin, even until the latter is removed from the blood by the kidneys. The main reason CO has such an adverse effect is that it cancels some haemoglobin, molecule for molecule, and that molecule of haemoglobin is never resuscitated. [[User:Dolphin51|<i style="color: green;">''Dolphin''</i>]] ''([[User talk:Dolphin51|<span style="color: blue;">t</span>]])'' 03:40, 8 March 2020 (UTC)

::No, CO isn't an [[irreversible inhibitor]]. See [[carboxyhemoglobin]]. The problem is that CO has a much greater affinity for hemoglobin than oxygen, so oxygen at ordinary concentrations doesn't displace CO quickly. --[[Special:Contributions/47.146.63.87|47.146.63.87]] ([[User talk:47.146.63.87|talk]]) 06:28, 8 March 2020 (UTC)

:{{slink|Red blood cell|Life cycle}}: red blood cells have a lifetime of about 4 months in the blood, after which they're broken down. But as I noted above, CO doesn't stay bound forever. The problem is while it is bound, the hemoglobin can't carry oxygen, and meanwhile your cells need oxygen, so if enough hemoglobin gets "poisoned" by CO you start suffering hypoxia. Cool fact: your body [[Gaseous signaling molecule#Carbon monoxide|produces some CO itself]] as a signaling molecule. --[[Special:Contributions/47.146.63.87|47.146.63.87]] ([[User talk:47.146.63.87|talk]]) 06:28, 8 March 2020 (UTC)

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