XYY syndrome: Difference between revisions - Wikipedia


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* {{cite book |author=Borgaonkar, Diagamber S. |year=1978 |chapter=Cytogenic screening of community-dwelling males |pages=[https://archive.org/details/geneticissuesinp00cohe/page/215 215–234] |editor1=Cohen, Bernice H. |editor2=Lilienfield, Abraham M. |editor3=Huang, P. C. |title=Genetic issues in public health and medicine |location=Springfield, Ill. |publisher=Charles C Thomas |isbn=978-0-398-03659-1 |chapter-url=https://archive.org/details/geneticissuesinp00cohe/page/215 }}

* {{cite book |author=Washington, Harriet A. |year=2004 |chapter=Born for evil? Stereotyping the karyotype: A case history in the genetics of aggressiveness |editor1=Roelcke, Volker |editor2=Maio, Giovanni |title=Twentieth century ethics of human subjects research : historical perspectives on values, practices, and regulations |pages=319–334 |location=Stuttgart |publisher=[[Franz Steiner Verlag]] |isbn=978-3-515-08455-0}}

* {{cite book |author=Washington, Harriet A. |year=2006 |chapter=The children's crusade: research targets young African Americans |title=Medical apartheid : the dark history of experimentation on black Americans from colonial times to the present |pages=[https://archive.org/details/medicalapartheid00wash/page/279 279–283] |location=New York |publisher=[[Doubleday (publisher)|Doubleday]] |isbn=978-0-385-50993-0 |chapter-url=https://archive.org/details/medicalapartheid00wash/page/279 }}</ref> Concurrently, through 1974, psychologist [[John Money]] at Johns Hopkins Hospital experimented on thirteen XYY boys and men (ages 15 to 37) in an unsuccessful attempt to treat their history of behavior problems by [[chemical castration]] using high-dose [[Depo-Provera]]—with side-effects of weight gain (avg. 26&nbsp;lbs.) and suicide.<ref name="Pyeritz 1977"/><ref>{{cite journal|last1=Blumer|first1=Dietrich|last2=Migeon|first2=Claude|date=February 1975|title=Hormone and hormonal agents in the treatment of aggression|journal=[[Journal of Nervous and Mental Disease|J Nerv Ment Dis]]|volume=160|issue=2|pages=127–137|pmid=123269|doi=10.1097/00005053-197502000-00007|s2cid=25125941}}

* {{cite journal |author1=Money, John |author-link1=John Money |author2=Wiedeking, Claus |author3=Walker, Paul |author4=Migeon, Claude |author5=Meyer, Walter |author6=Borgaonkar, Digamber |year=1975 |title=47,XYY and 46,XY males with antisocial and/or sex-offending behavior: antiandrogen therapy plus counseling |journal=Psychoneuroendocrinology |volume=1 |issue=2 |pages=165–176 |pmid=1234655 |doi=10.1016/0306-4530(75)90008-6|s2cid=41068306 }}—two other XYY boys (age 10) were deemed too young for chemical castration.

* {{cite journal |author1=Wiedeking, Claus |author2=Money, John |author3=Walker, Paul |date=May 1979 |title=Follow-up of 11 XYY males with impulsive and/or sex-offending behaviour |journal=[[Psychological Medicine|Psychol Med]] |volume=9 |issue=2 |pages=287–292 |pmid=472074 |doi=10.1017/S0033291700030786|s2cid=25174397 }}</ref>

In the late 1960s and early 1970s, screening of consecutive newborns for sex chromosome abnormalities was undertaken at seven centers worldwide: in [[Denver]] (Jan 1964–1974), [[Edinburgh]] (Apr 1967–Jun 1979), [[New Haven]] (Oct 1967–Sep 1968), [[Toronto]] (Oct 1967–Sep 1971), [[Aarhus]] (Oct 1969–Jan 1974, Oct 1980–Jan 1989), [[Winnipeg]] (Feb 1970–Sep 1973), and [[Boston]] (Apr 1970–Nov 1974).<ref name="March of Dimes">{{cite book |editor1=Robinson, Arthur |editor2=Lubs, Herbert A. |editor3=Bergsma, Daniel |year=1979 |title=Sex chromosome aneuploidy: prospective studies on children|series=Birth defects original article series '''15''' (1) |location=New York |publisher=[[John Wiley & Sons|Alan R. Liss]] |isbn=978-0-8451-1024-9}}