American Association may refer to:
- American Association (American football), a minor professional American football league that existed from 1936 to 1950
- American Association (1882–1891), a major league active from 1882 to 1891
- American Association (1902–1997), a minor league active from 1902 to 1962 and 1969 to 1997
- American Association of Professional Baseball, an independent league founded in 2006
- American Association, Limited, Office Building, a historic building in Middlesboro, Kentucky, U.S.
- Numerous professional organizations whose formal names begin with American Association can be found via the "All pages with titles beginning" link below