CCDC6


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Coiled-coil domain-containing protein 6 is a protein that in humans is encoded by the CCDC6 gene.[5][6][7]

CCDC6
Identifiers
AliasesCCDC6, D10S170, H4, PTC, TPC, TST1, coiled-coil domain containing 6
External IDsOMIM: 601985; MGI: 1923801; HomoloGene: 34786; GeneCards: CCDC6; OMA:CCDC6 - orthologs
Gene location (Human)
Chromosome 10 (human)
Chr.Chromosome 10 (human)[1]

Chromosome 10 (human)

Genomic location for CCDC6

Genomic location for CCDC6

Band10q21.2Start59,788,747 bp[1]
End59,906,556 bp[1]
Gene location (Mouse)
Chromosome 10 (mouse)
Chr.Chromosome 10 (mouse)[2]

Chromosome 10 (mouse)

Genomic location for CCDC6

Genomic location for CCDC6

Band10|10 B5.3Start69,932,951 bp[2]
End70,029,030 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • parotid gland

  • buccal mucosa cell

  • skin of thigh

  • skin of hip

  • middle temporal gyrus

  • saphenous vein

  • parietal pleura

  • caput epididymis

  • jejunal mucosa
Top expressed in
  • zygote

  • secondary oocyte

  • primary oocyte

  • vastus lateralis muscle

  • knee joint

  • tibialis anterior muscle

  • ankle

  • extensor digitorum longus muscle

  • triceps brachii muscle

  • gastrocnemius muscle
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

8030

76551

Ensembl

ENSG00000108091

ENSMUSG00000048701

UniProt

Q16204

D3YZP9

RefSeq (mRNA)

NM_005436

NM_001111121

RefSeq (protein)

NP_005427

NP_001104591

Location (UCSC)Chr 10: 59.79 – 59.91 MbChr 10: 69.93 – 70.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CCDC6 has been shown to interact with PPP4C.[8][9]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000108091Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048701Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Grieco M, Cerrato A, Santoro M, Fusco A, Melillo RM, Vecchio G (Sep 1994). "Cloning and characterization of H4 (D10S170), a gene involved in RET rearrangements in vivo". Oncogene. 9 (9): 2531–5. PMID 8058316.
  6. ^ Anne-Spence M, Falk CT, Neiswanger K, Field LL, Marazita ML, Allen FH, Siervogel RM, Roche AF, Crandall BF, Sparkes RS (Sep 1984). "Estimating the recombination frequency for the PTC-Kell linkage". Human Genetics. 67 (2): 183–6. doi:10.1007/BF00272997. PMID 6745938. S2CID 8634962.
  7. ^ "Entrez Gene: CCDC6 coiled-coil domain containing 6".
  8. ^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  9. ^ Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault M, Gingras AC (Oct 2008). "PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4". The Journal of Biological Chemistry. 283 (43): 29273–84. doi:10.1074/jbc.M803443200. PMC 2662017. PMID 18715871.