Artesunate/pyronaridine: Difference between revisions - Wikipedia

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It has also been studied as a potential anticancer drug<ref>{{cite journal | vauthors = Villanueva PJ, Martinez A, Baca ST, DeJesus RE, Larragoity M, Contreras L, Gutierrez DA, Varela-Ramirez A, Aguilera RJ | display-authors = 6 | title = Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosis | journal = PloS One | volume = 13 | issue = 11 | pages = e0206467 | date = 2018-11-05 | pmid = 30395606 | pmc = 6218039 | doi = 10.1371/journal.pone.0206467 | url = https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206467 }}</ref>, treatment for Ebola<ref>{{cite journal | vauthors = Lane TR, Massey C, Comer JE, Anantpadma M, Freundlich JS, Davey RA, Madrid PB, Ekins S | display-authors = 6 | title = Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection | journal = PLoS Neglected Tropical Diseases | volume = 13 | issue = 11 | pages = e0007890 | date = November 2019 | pmid = 31751347 | pmc = 6894882 | doi = 10.1371/journal.pntd.0007890 }}</ref>

The combination of pyronaridin and altesunate is being studied as a possible treatment for moderate to severe SARS-COV-2. to moderate to severe SARS-COV-2.<ref>{{Cite journal|last=Krishna|first=Sanjeev|last2=Augustin|first2=Yolanda|last3=Wang|first3=Jigang|last4=Xu|first4=Chengchao|last5=Staines|first5=Henry M.|last6=Platteeuw|first6=Hans|last7=Kamarulzaman|first7=Adeeba|last8=Sall|first8=Amadou|last9=Kremsner|first9=Peter|date=2021-01-19|title=Repurposing Antimalarials to Tackle the COVID-19 Pandemic: (Trends in Parasitology 37, 8–11; 2021)|url=https://www.cell.com/trends/parasitology/abstract/S1471-4922(20)30364-0|journal=Trends in Parasitology|language=English|volume=0|issue=0|doi=10.1016/j.pt.2020.12.009|issn=1471-4922}}</ref>

== References ==