PARC (gene)

Cullin-9 is a protein that in humans is encoded by the CUL9 gene.^[5][6][7][8]

CUL9
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2JUF
Identifiers
Aliases	CUL9, H7AP1, PARC, 1810035I07Rik, Cul-9, mKIAA0708, cullin 9
External IDs	OMIM: 607489; MGI: 1925559; HomoloGene: 56696; GeneCards: CUL9; OMA:CUL9 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p21.1 Start 43,182,184 bp[1] End 43,224,587 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 C Start 46,811,498 bp[2] End 46,857,314 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right testis left testis right frontal lobe right hemisphere of cerebellum anterior pituitary granulocyte right lobe of thyroid gland skin of abdomen skin of leg spleen Top expressed in neural layer of retina dentate gyrus of hippocampal formation granule cell primary visual cortex superior frontal gyrus muscle of thigh spermatocyte right kidney cerebellar cortex proximal tubule lumbar subsegment of spinal cord More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding protein binding ATP binding ubiquitin protein ligase binding metal ion binding transferase activity Cellular component cytoplasm cullin-RING ubiquitin ligase complex cytosol Biological process microtubule cytoskeleton organization ubiquitin-dependent protein catabolic process regulation of mitotic nuclear division protein ubiquitination post-translational protein modification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23113 78309 Ensembl ENSG00000112659 ENSMUSG00000040327 UniProt Q8IWT3 Q80TT8 RefSeq (mRNA) NM_015089 NM_001081335 RefSeq (protein) NP_055904 n/a Location (UCSC) Chr 6: 43.18 – 43.22 Mb Chr 17: 46.81 – 46.86 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

PARC (gene) has been shown to interact with P53.^[7]