Derlin-2


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Derlin-2 is a protein that in humans is encoded by the DERL2 gene.[5][6][7]

DERL2
Identifiers
AliasesDERL2, F-LAN-1, F-LANa, FLANa, CGI-101, DERtrin-2, derlin 2, derlin-2
External IDsOMIM: 610304; MGI: 2151483; HomoloGene: 9356; GeneCards: DERL2; OMA:DERL2 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]

Chromosome 17 (human)

Genomic location for DERL2

Genomic location for DERL2

Band17p13.2Start5,471,254 bp[1]
End5,486,811 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]

Chromosome 11 (mouse)

Genomic location for DERL2

Genomic location for DERL2

Band11 B4|11 43.21 cMStart70,897,990 bp[2]
End70,910,667 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right testis

  • left testis

  • body of pancreas

  • Achilles tendon

  • right lobe of liver

  • parotid gland

  • mucosa of transverse colon

  • olfactory zone of nasal mucosa

  • right adrenal gland

  • granulocyte
Top expressed in
  • cumulus cell

  • left lobe of liver

  • seminal vesicula

  • lacrimal gland

  • decidua

  • right lung lobe

  • stroma of bone marrow

  • islet of Langerhans

  • right kidney

  • yolk sac
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51009

116891

Ensembl

ENSG00000072849

ENSMUSG00000018442

UniProt

Q9GZP9

Q8BNI4

RefSeq (mRNA)

NM_001304777
NM_001304779
NM_016041

NM_001291146
NM_001291147
NM_001291148
NM_033562

RefSeq (protein)

NP_001291706
NP_001291708
NP_057125

NP_001278075
NP_001278076
NP_001278077
NP_291040

Location (UCSC)Chr 17: 5.47 – 5.49 MbChr 11: 70.9 – 70.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000072849Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000018442Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
  6. ^ Ying H, Yu Y, Xu Y (Aug 2001). "Cloning and characterization of F-LANa, upregulated in human liver cancer". Biochem Biophys Res Commun. 286 (2): 394–400. doi:10.1006/bbrc.2001.5390. PMID 11500051.
  7. ^ "Entrez Gene: DERL2 Der1-like domain family, member 2".