[Democratic Republic of the Congo: between civil war and the Marburg virus. International Committee of Technical and Scientific Coordination of the Durba Epidemic] - PubMed
E Bertherat 1 , A Talarmin, H Zeller
Article Images[Article in French]
Affiliations
- PMID: 10546197
[Democratic Republic of the Congo: between civil war and the Marburg virus. International Committee of Technical and Scientific Coordination of the Durba Epidemic]
[Article in French]
E Bertherat et al. Med Trop (Mars). 1999.
Abstract
Because the epidemiology of viral hemorrhagic fever is unclear, each outbreak is a spectacular event that focuses the attention of the international scientific community. When an epidemic of Marburg virus disease occurred in the Durba region located in the northeastern part of the People's Republic of the Congo, 23 scientists were sent from 12 different countries. Sixty of the 73 people infected died. The first case was observed in December 1998 and the last in May 1999. Because of political unrest in the country, the outbreak was not reported immediately and most data was collected by observers retrospectively. However Marburg virus infection was confirmed in 5 of 16 patients in whom testing was performed and person-to-person transmission was demonstrated. Thus the Durba outbreak was the first epidemic of Marburg virus disease not involving laboratory contamination. Initial epidemiologic findings suggest that the first cases involved miners who were probably infected by contact with an animal reservoir such as bats. Further studies to determine seroprevalence in the general population and virologic testing on animals captured in the zone should provide answers to these questions.
Similar articles
-
Marburg hemorrhagic fever associated with multiple genetic lineages of virus.
Bausch DG, Nichol ST, Muyembe-Tamfum JJ, Borchert M, Rollin PE, Sleurs H, Campbell P, Tshioko FK, Roth C, Colebunders R, Pirard P, Mardel S, Olinda LA, Zeller H, Tshomba A, Kulidri A, Libande ML, Mulangu S, Formenty P, Grein T, Leirs H, Braack L, Ksiazek T, Zaki S, Bowen MD, Smit SB, Leman PA, Burt FJ, Kemp A, Swanepoel R; International Scientific and Technical Committee for Marburg Hemorrhagic Fever Control in the Democratic Republic of the Congo. Bausch DG, et al. N Engl J Med. 2006 Aug 31;355(9):909-19. doi: 10.1056/NEJMoa051465. N Engl J Med. 2006. PMID: 16943403
-
[Lessons from the Marburg virus epidemic in Durba, Democratic Republic of the Congo (1998-2000)].
Zeller H. Zeller H. Med Trop (Mars). 2000;60(2 Suppl):23-6. Med Trop (Mars). 2000. PMID: 11100456 Review. French. No abstract available.
-
Colebunders R, Sleurs H, Pirard P, Borchert M, Libande M, Mustin JP, Tshomba A, Kinuani L, Olinda LA, Tshioko F, Muyembe-Tamfum JJ. Colebunders R, et al. J Infect. 2004 May;48(4):347-53. doi: 10.1016/S0163-4453(03)00122-1. J Infect. 2004. PMID: 15066337
-
Colebunders R, Tshomba A, Van Kerkhove MD, Bausch DG, Campbell P, Libande M, Pirard P, Tshioko F, Mardel S, Mulangu S, Sleurs H, Rollin PE, Muyembe-Tamfum JJ, Jeffs B, Borchert M; International Scientific and Technical Committee "DRC Watsa/Durba 1999 Marburg Outbreak Investigation Group". Colebunders R, et al. J Infect Dis. 2007 Nov 15;196 Suppl 2:S148-53. doi: 10.1086/520543. J Infect Dis. 2007. PMID: 17940943
-
Development of vaccines for Marburg hemorrhagic fever.
Bausch DG, Geisbert TW. Bausch DG, et al. Expert Rev Vaccines. 2007 Feb;6(1):57-74. doi: 10.1586/14760584.6.1.57. Expert Rev Vaccines. 2007. PMID: 17280479 Review.
Cited by
-
Rise of Marburg virus in Africa: a call for global preparedness.
Okesanya OJ, Manirambona E, Olaleke NO, Osumanu HA, Faniyi AA, Bouaddi O, Gbolahan O, Lasala JJ, Lucero-Prisno DE 3rd. Okesanya OJ, et al. Ann Med Surg (Lond). 2023 Sep 1;85(10):5285-5290. doi: 10.1097/MS9.0000000000001257. eCollection 2023 Oct. Ann Med Surg (Lond). 2023. PMID: 37811021 Free PMC article.
-
Emergence of Marburg virus: a global perspective on fatal outbreaks and clinical challenges.
Srivastava S, Sharma D, Kumar S, Sharma A, Rijal R, Asija A, Adhikari S, Rustagi S, Sah S, Al-Qaim ZH, Bashyal P, Mohanty A, Barboza JJ, Rodriguez-Morales AJ, Sah R. Srivastava S, et al. Front Microbiol. 2023 Sep 13;14:1239079. doi: 10.3389/fmicb.2023.1239079. eCollection 2023. Front Microbiol. 2023. PMID: 37771708 Free PMC article. Review.
-
Mane Manohar MP, Lee VJ, Chinedum Odunukwe EU, Singh PK, Mpofu BS, Oxley Md C. Mane Manohar MP, et al. Cureus. 2023 Jul 17;15(7):e42014. doi: 10.7759/cureus.42014. eCollection 2023 Jul. Cureus. 2023. PMID: 37593293 Free PMC article. Review.
-
Environmental and health risks posed to children by artisanal gold mining: A systematic review.
Allan-Blitz LT, Goldfine C, Erickson TB. Allan-Blitz LT, et al. SAGE Open Med. 2022 Feb 9;10:20503121221076934. doi: 10.1177/20503121221076934. eCollection 2022. SAGE Open Med. 2022. PMID: 35173966 Free PMC article. Review.
-
STAT-1 Knockout Mice as a Model for Wild-Type Sudan Virus (SUDV).
Escaffre O, Juelich TL, Neef N, Massey S, Smith J, Brasel T, Smith JK, Kalveram B, Zhang L, Perez D, Ikegami T, Freiberg AN, Comer JE. Escaffre O, et al. Viruses. 2021 Jul 17;13(7):1388. doi: 10.3390/v13071388. Viruses. 2021. PMID: 34372594 Free PMC article.