Introduction to super-resolution microscopy - PubMed


Masahito Yamanaka 1 ,

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Review

doi: 10.1093/jmicro/dfu007. Epub 2014 Mar 25.

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Review

Introduction to super-resolution microscopy

Masahito Yamanaka et al. Microscopy (Oxf). 2014 Jun.

Abstract

In this review, we introduce the principles of spatial resolution improvement in super-resolution microscopies that were recently developed. These super-resolution techniques utilize the interaction of light and fluorescent probes in order to break the diffraction barrier that limits spatial resolution. The imaging property of each super-resolution technique is also compared with the corresponding conventional one. Typical applications of the super-resolution techniques in biological research are also introduced.

Keywords: PALM; SAX; SIM; STED; STORM; Super-resolution microscopy.

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