Genetic mechanisms of critical illness in Covid-19

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19 December 2020

title

Genetic mechanisms of critical illness in Covid-19 (English)

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19 December 2020

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genome-wide association study

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based on heuristic

inferred from abstract

author

Erola Pairo-Castineira

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19 December 2020

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19 December 2020

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19 December 2020

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19 December 2020

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19 December 2020

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19 December 2020

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19 December 2020

Viktoria-Eleni Gountouna

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19 December 2020

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19 December 2020

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19 December 2020

Athanasios Kousathanas

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19 December 2020

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19 December 2020

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19 December 2020

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19 December 2020

Peter Horby

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19 December 2020

Sara Clohisey

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19 December 2020

David Harrison

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19 December 2020

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19 December 2020

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19 December 2020

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19 December 2020

Alistair Nichol

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19 December 2020

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19 December 2020

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19 December 2020

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19 December 2020

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19 December 2020

publication date

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19 December 2020

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17 May 2021

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https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Cohort Profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness.

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Recent genomic heritage in Scotland

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Next-generation genotype imputation service and methods

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Fast and accurate imputation of summary statistics enhances evidence of functional enrichment

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Integrating predicted transcriptome from multiple tissues improves association detection

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Genetic effects on gene expression across human tissues

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Generation Scotland: the Scottish Family Health Study; a new resource for researching genes and heritability

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Causal associations between risk factors and common diseases inferred from GWAS summary data

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

MAGMA: generalized gene-set analysis of GWAS data

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Partitioning heritability by functional annotation using genome-wide association summary statistics

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

An atlas of genetic correlations across human diseases and traits

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

The UCSC Genome Browser Database: update 2006

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Comparative transcriptome analysis reveals the intensive early-stage responses of host cells to SARS-CoV-2 infection

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Single-cell landscape of immunological responses in patients with COVID-19

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Upper airway gene expression reveals suppressed immune responses to SARS-CoV-2 compared with other respiratory viruses

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro

17 May 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-020-03065-Y

Trans-ethnic analysis reveals genetic and non-genetic associations with COVID-19 susceptibility and severity

17 May 2021

0 references

Robust, reproducible clinical patterns in hospitalised patients with COVID-19

0 references

Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19

0 references

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

0 references

Identifiers

DOI

10.1038/S41586-020-03065-Y

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33307546%20AND%20SRC:MED&resulttype=core&format=json

19 December 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33307546%20AND%20SRC:MED&resulttype=core&format=json